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KMID : 0861020080230030175
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Korea Journal of Herbology
2008 Volume.23 No. 3 p.175 ~ p.180
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Antidiabetic Effect of Glechoma Longituba (Nakai) Kupr in Diabetic Rats induced by Streptozotocin
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Lee Kyung-Jin
Kim Ho-Cheol
Bu Young-Min
Ham In-Hye
Choi Ho-Young
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Abstract
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Objecitivies : While Glechoma longituba (Nakai) Kupr(GL) has been known as a antiinflammatory, antidiabetic and antihypertension medicine in korea traditional medicine, there has been only a few researches about it in Korea. Thus, we examined antidiabetic effect of GL in diabetic rats induced by streptozotocin
Methods : To verify the effects of GL on serum glucose, creatinine, BUN, total cholesterol and triglyceride through streptozotocin-induced diabetic rats, some rats were injected 1 time with 55mg/kg streptozotocin intraperitoneally to induce diabetes, and other rats were injected with buffer I.P. as control group.
Results : GL extracts significantly reduced the amount of serum glucose, BUN, creatinine, and triglyceride level in diabetics rats induced by streptozotocin.
Conclusions : According to above result, Glechoma longituba was expected to be applied to the treatment of diabetes mellitus.
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KEYWORD
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Glechoma Longituba, streptozotocin, diabetes mellitus, DM
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